Übersichtsarbeit
Julia Welzel
Optische Kohärenztomographie zur nichtinvasiven Diagnostik in der Dermatologie
Optical coherence tomography for non-invasive diagnostics in dermatology
Keywords | Summary | Correspondence | Literature
Keywords
non-invasive diagnosis, optical coherence tomography, skin cancer, therapy monitoring, wound healing
Schlüsselworte
Hautkrebs, nichtinvasive Diagnostik, Optische Kohärenztomographie, Therapiemonitoring, Wundheilung
Summary
Optical coherence tomography is a non-invasive imaging method. It provides in vivo real-time cross-sectional images of several millimetres length and a depth penetration down to lower parts of the dermis. the epidermis, upper dermis, blood vessels and adnex structures can be distinguished. Oct allows diagnosis of basal cell carcinomas and actinic keratoses as well as monitoring of inflammatory skin diseases and wound healing. In cosmetic dermatology, Oct can be used for objective quantification of treatment effects. Especially results of laser therapy can be visualized and evaluated using this method.
Zusammenfassung
Die optische Kohärenztomographie ist eine nichtinvasive bildgebende Methode. mit ihr lassen sich in vivo Schnittbilder von einigen millimetern Breite und einer tiefe bis in die mittlere Dermis in Echtzeit aufnehmen. An den Bildern können Epidermis, obere Dermis, Blutgefäße und Adnexe differenzieret werden. Die Methode eignet sich zur Diagnostik von Basalzellkarzinomen und aktinischen Keratosen sowie zur Verlaufsbeobachtung entzündlicher Dermatosen und von Wundheilung. Im Bereich der kosmetischen Dermatologie sind Einsatzmöglichkeiten zur Objektivierung und Quantifizierung von Therapieeffekten interessant. Insbesondere Effekte einer Lasertherapie lassen sich mit dieser Methode visualisieren und evaluieren.
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Korrespondenz-Adresse
Prof. Dr. med. Julia Welzel
''Klinik für Dermatologie und Allergologie
Sauerbruchstraße 6
D-86179 Augsburg
E-mail: julia.welzel@klinikum-augsburg.de
Literatur
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